Article

Splenocytes with fucosylation deficiency promote T cell proliferation and differentiation through thrombospondin-1 downregulation

2023-09-08

Abstract excerpt

Fucosylation plays a critical role in cell-to-cell interactions and disease progression. However, the effects of fucosylation on splenocytes and their interactions with T cells remain unclear. In this study, we aimed to explore the transcriptome profiles of splenocytes deficient in fucosyltransferase (FUT) 1, an enzyme that mediates fucosylation, and investigate their impact on the proliferation and differentiatio...

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Literature Corpus work: 38db68ae-c7af-5622-9b05-badaa3d3124c
DOI: 10.22541/au.169418473.38790003/v1

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