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Genetic Diseases of Fucosylation: Insights from Model Organisms

3 Jul 2025

Abstract excerpt

Fucosylation plays a fundamental role in maintaining cellular functions and biological processes across all animals. As a form of glycosylation, it involves the biochemical addition of fucose, a six-carbon monosaccharide, to biological molecules like lipids, proteins, and glycan chains. This modification is essential for optimizing cellular interactions required for receptor-ligand binding, cell adhesion, immune...

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PMID: 40725456
DOI: 10.3390/genes16070800

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