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Conveying glycan information into T‐cell homeostatic programs: a challenging role for galectin‐1 in inflammatory and tumor microenvironments

29 Jun 2009

Abstract excerpt

The immune system has evolved sophisticated mechanisms composed of several checkpoints and fail-safe processes that enable it to orchestrate innate and adaptive immunity, while at the same time limiting aberrant or unfaithful T-cell function. These multiple regulatory pathways take place during the entire life-span of T cells including T-cell development, homing, activation, and differentiation. Galectin-1, an...

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PMID: 19594634
DOI: 10.1111/j.1600-065x.2009.00787.x

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