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FUT8-mediated core fucosylation modulates growth-related functions of LRP1 in liver cancer cells

2026-04-13

Abstract excerpt

<h4>Summary</h4> Fucosylation is a cancer-associated glycosylation change, and core fucosylation of N-glycans catalyzed by the α1,6-fucosyltransferase FUT8, has been closely linked to tumor progression, metastasis, drug resistance, and poor prognosis. However, the core-fucosylated proteins that directly support hepatocarcinogenesis are not fully defined. In a KRAS-G12D-driven mouse liver cancer model, we observed...

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Literature Corpus work
107344ec-afac-50a6-aa7d-02f885f923e1
DOI
10.64898/2026.04.09.717446
Open publication

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FUT8-mediated core fucosylation modulates growth-related functions of LRP1 in liver cancer cellsDOI 10.64898/2026.04.09.717446
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