Article

Spatial transcriptomics reveals molecular dysfunction associated with Lewy pathology

2023-05-17

Abstract excerpt

Lewy pathology composed of α-synuclein is the key pathological hallmark of Parkinson’s disease (PD), found both in dopaminergic neurons that control motor function, and throughout cortical regions that control cognitive function. Recent work has investigated which dopaminergic neurons are most susceptible to death, but little is known about which neurons are vulnerable to developing Lewy pathology and what molecul...

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Literature Corpus work: 37feb9fb-d022-5299-91a5-6b0e5e961ba5
DOI: 10.1101/2023.05.17.541144

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