Article

Single-cell transcriptomic and proteomic analysis of Parkinson’s disease Brains

2022-02-14

Abstract excerpt

Parkinson’s disease (PD) is a prevalent neurodegenerative disorder where recent evidence suggests pathogenesis may be mediated by inflammatory processes. The molecular architecture of the disease remains to be fully elucidated. We performed single-nucleus transcriptomics and unbiased proteomics using postmortem tissue obtained from the prefrontal cortex of 12 individuals with late-stage PD and age-matched controls...

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Literature Corpus work: 809a0d78-0227-5015-b0a0-9f405d716a26
DOI: 10.1101/2022.02.14.480397

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