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The SWI/SNF PBAF complex facilitates REST occupancy at repressive chromatin

2024-08-23

Abstract excerpt

<h4>Summary</h4> Multimeric SWI/SNF chromatin remodelers assemble into discrete conformations with unique complex functionalities difficult to dissect. Distinct cancers harbor mutations in specific subunits, altering the chromatin landscape, such as the PBAF-specific component ARID2 in melanoma. Here, we performed comprehensive epigenomic profiling of SWI/SNF complexes and their associated chromatin states in mel...

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Identifiers and source

Literature Corpus work
376c2611-921c-58d9-a040-34cbe0ecf79d
DOI
10.1101/2024.08.23.609212
Open publication

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The SWI/SNF PBAF complex facilitates REST occupancy at repressive chromatinDOI 10.1101/2024.08.23.609212
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