Article

Interpreting coronary artery disease GWAS results: A functional genomics approach assessing biological significance

2020-12-21

Abstract excerpt

Genome-wide association studies (GWAS) have implicated 58 loci in coronary artery disease (CAD). However, the biological basis for these associations, the relevant genes, and causative variants often remain uncertain. Since the vast majority of GWAS loci reside outside coding regions, most exert regulatory functions. Here we explore the complexity of each of these loci, using tissue specific RNA sequencing data fr...

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Literature Corpus work: 376a2e4c-9324-5a63-9047-8ad806a2128d
DOI: 10.1101/2020.12.21.423751

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