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Article

Large-scale gene-centric analysis identifies novel variants for coronary artery disease.

PLoS genetics - 1 Sept 2011

Abstract excerpt

Coronary artery disease (CAD) has a significant genetic contribution that is incompletely characterized. To complement genome-wide association (GWA) studies, we conducted a large and systematic candidate gene study of CAD susceptibility, including analysis of many uncommon and functional variants. We examined 49,094 genetic variants in ∼2,100 genes of cardiovascular relevance, using a customised gene array in...

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Identifiers

PMID: 21966275
DOI: 10.1371/journal.pgen.1002260
PMCID: PMC3178591

Genes

CAD
ABCG5
ABCG8
LIPA
LPA
TRIB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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