Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide studies of gene expression relevant to coronary artery disease.

Current opinion in cardiology - 1 May 2012

Hsu Jeffrey, Smith Jonathan D

Abstract excerpt

PURPOSE OF REVIEW: Genome-wide association studies have led to the discovery of many single nucleotide polymorphisms (SNPs) associated with coronary artery disease (CAD). However, many of these SNPs are in between genes (intergenic), and presumably function through the regulation of gene expression. Microarrays that measure the expression of thousands of mRNAs have allowed investigators to study how genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to RNA, Messenger
Share to Coronary Artery Disease
Share to Gene Expression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Molecular Biology

Share to Oligonucleotide Array Sequence Analysis

Share to Risk Assessment

Share to United States

Source

Open in PubMed Open full text

Identifiers

PMID: 22476029
DOI: 10.1097/HCO.0b013e3283522198
PMCID: PMC3332306

Genes

CAD
SORT1
PDGFD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide studies of gene expression relevant to coronary artery disease.PMID 22476029Read ↗

Interpreting coronary artery disease GWAS results: A functional genomics approach assessing biological significanceSemantic proximity Read ↗

Interpreting coronary artery disease GWAS results: A functional genomics approach assessing biological significance.Semantic proximity Read ↗

CELSR2-PSRC1-SORT1 gene expression and association with coronary artery disease and plasma lipid levels in an Asian Indian cohort.Semantic proximity Read ↗

Associations of Gene Expressions in Liver and Blood Cells and Circulating Proteins With Coronary Artery DiseaseSemantic proximity Read ↗

Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease.Semantic proximity Read ↗

Gene expression analysis of cardiovascular diseases: novel insights into biology and clinical applications.Semantic proximity Read ↗

PSRC1 May Affect Coronary Artery Disease Risk by Altering CELSR2, PSRC1, and SORT1 Gene Expression and Circulating Granulin and Apolipoprotein B Protein LevelsSemantic proximity Read ↗

Transcriptome wide association study of coronary artery disease identifies novel susceptibility genesSemantic proximity Read ↗

Transcriptome wide association study of coronary artery disease identifies novel susceptibility genesSemantic proximity Read ↗

Genome-wide association studies identify new targets in cardiovascular disease.Semantic proximity Read ↗

Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies.Semantic proximity Read ↗

Genetic regulation of human aortic smooth muscle cell gene expression and splicing predict causal coronary artery disease genesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.