Article

DNA i-motif levels are overwhelmingly depleted in living human cells: insights from in-cell NMR.

2023-12-19

Abstract excerpt

<title>Abstract</title> <p>I-Motifs (iM) are non-canonical DNA structures potentially forming in the accessible, single-stranded, cytosine-rich genomic regions with regulatory roles. Chromatin, protein interactions, and intracellular properties seem to govern iM formation at sites with i-motif formation propensity (iMFPS) in human cells, yet their specific contributions remain unclear. Using in-cell NMR with olig...

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Literature Corpus work: 9645a9b6-6cfd-5f8a-95e1-613359f2de42
DOI: 10.21203/rs.3.rs-3734993/v1

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