Article

An Atlas of Short Linear Motif-Mediated Human Protein-Protein Interactions

2026-07-06

Abstract excerpt

Short linear motifs (SLiMs) within intrinsically disordered protein regions mediate transient interactions crucial for cell physiology 1 . However, the global interaction landscape of human SLiMs remains largely uncharted. Here we present the Atlas of SLiM-mediated Human protein-protein Interactions (ASHI), which maps more than 20,000 interactions by screening over 800 human protein domains against a library of o...

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Literature Corpus work: e96b778a-bed5-5e63-af17-bdbeb7c9f8e9
DOI: 10.64898/2026.07.03.735260

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