Article

Gene regulatory network (GRN) embedded agents connect cellular decision making to human pluripotent stem cell derived germ layer-like pattern formation

2020-10-07

Abstract excerpt

<h4>ABSTRACT</h4> The emergence of germ layers in embryos during gastrulation is a key developmental milestone. How morphogenetic signals engage the regulatory networks responsible for early embryonic tissue patterning is incompletely understood. To understand this, we developed a gene regulatory network (GRN) model of human pluripotent stem cell (hPSC) lineage commitment and embedded it into ‘cellular’ agents th...

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Literature Corpus work: 36be89cc-0b9f-502a-82bc-2abe5af80c06
DOI: 10.1101/2020.10.06.327650

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Gene regulatory network (GRN) embedded agents connect cellular decision making to human pluripotent stem cell derived germ layer-like pattern formationDOI 10.1101/2020.10.06.327650Read

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