Article
Neuroepithelial organoid patterning is mediated by a neighborhood watch mechanism.
Cell reports - 28 Nov 2023
Abdel Fattah Abdel Rahman, Grebenyuk Sergei, de Rooij Laura P M H, Salmon Idris, Ranga Adrian
Abstract excerpt
During epithelial tissue patterning, morphogens operate across multiple length scales to instruct cell identities. However, how cell fate changes are coordinated over these scales to establish spatial organization remains poorly understood. Here, we use human neural tube organoids as models of epithelial patterning and develop an in silico approach to define conditions permissive to patterning. By systematically...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.