Article

Reg3g ameliorates Tacrolimus-induced pancreatic β cell dysfunction by restoring mitochondrial function

2021-03-28

Abstract excerpt

<h4>Background: </h4> and Purpose: Tacrolimus (Tac) induces pancreatic β cell dysfunction, causing new-onset diabetes mellitus (NODM) after transplantation. Reg3g is a member of the pancreatic regenerative gene family, as reported to improve type 1 diabetes by promoting β cell regeneration. Here, we aim to investigate the role and approach of Reg3g in reversing Tac-induced β cell dysfunction and NODM in mice. Expe...

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Literature Corpus work: 367de9ae-5c0b-5149-9486-e569f3a86646
DOI: 10.22541/au.161695374.47072563/v1

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