Article

Triptolide Improves Endoplasmic Reticulum Stress-mediated Podocyte Apoptosis under High Glucose Conditions

2023-06-30

Abstract excerpt

<h4>Background: </h4> Diabetic kidney disease (DKD) is an important complication of diabetes in which endoplasmic reticulum stress (ERS) plays an important role and triptolide (TP) is effective in the treatment of DKD. To investigate the inhibition of ERS-mediated apoptosis in podocytes by TP in a high glucose environment in vivo and in vitro. Methods 1. DKD rat models were established by a high-fat, high-sugar d...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f423b8be-143c-5d4d-aacd-f22d65d82661
DOI: 10.21203/rs.3.rs-3114425/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Triptolide Improves Endoplasmic Reticulum Stress-mediated Podocyte Apoptosis under High Glucose ConditionsDOI 10.21203/rs.3.rs-3114425/v1Read

Research progress on ferroptosis in diabetic kidney diseaseSemantic proximity Read

Therapeutic opportunities for pancreatic β-cell ER stress in diabetes mellitusSemantic proximity Read

Role of ferroptosis inhibitors in the management of diabetesSemantic proximity Read

Ursodeoxycholic acid and 4-phenylbutyrate prevent endoplasmic reticulum stress-induced podocyte apoptosis in diabetic nephropathy.Semantic proximity Read

Can We Prevent Mitochondrial Dysfunction and Diabetic Cardiomyopathy in Type 1 Diabetes Mellitus? Pathophysiology and Treatment OptionsSemantic proximity Read

Epigenetics and endoplasmic reticulum in podocytopathy during diabetic nephropathy progressionSemantic proximity Read

Monogenic and syndromic diabetes due to endoplasmic reticulum stressSemantic proximity Read

High Glucose-Induced ROS-Accumulation in Zebrafish Larvae Leads to Mitochondria- Mediated ApoptosisSemantic proximity Read

[Endoplasmic reticulum stress and diabetes].Semantic proximity Read

Pathological β-Cell Endoplasmic Reticulum Stress in Type 2 Diabetes: Current Evidence.Semantic proximity Read

Review on pathophysiology and treatment of diabetic kidney disease.Semantic proximity Read

Types of cell death in diabetic cardiomyopathy: insights from animal modelsSemantic proximity Read