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Article

Pancreastatin is an endogenous peptide that regulates glucose homeostasis.

Physiological genomics - 15 Nov 2013

Valicherla Guru Raghavendra, Hossain Zakir, Mahata Sushil K, Gayen Jiaur R

Abstract excerpt

Pancreastatin (PST) is a regulatory peptide containing 49 amino acids, first isolated from porcine pancreas. Intracellular and extracellular processing of the prohormone Chromogranin A (Chga) results various bioactive peptides of which PST has dysglycemic activity. PST regulates glucose, lipid, and protein metabolism in liver and adipose tissues. It also regulates the secretion of leptin and expression of leptin...

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PMID: 24064537
DOI: 10.1152/physiolgenomics.00131.2013

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