Article

Transferability of genetic loci and polygenic scores for cardiometabolic traits in British Pakistanis and Bangladeshis

2021-06-24

Abstract excerpt

<h4>Background</h4> Individuals with South Asian ancestry have higher risk of heart disease than other groups in Western countries; however, most genetic research has focused on European-ancestry (EUR) individuals. It is unknown whether reported genetic loci and polygenic scores (PGSs) for cardiometabolic traits are transferable to South Asians, and whether PGSs have utility in clinical settings. <h4>Methods</h4>...

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Literature Corpus work: 3614e1c5-1570-5d76-a890-5a0269102b24
DOI: 10.1101/2021.06.22.21259323

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