Article

Transferability of European-derived cardiometabolic polygenic risk scores in the South Asians and their interplay with family history

2023-03-20

Abstract excerpt

<h4>Background & Aims</h4> We aimed to investigate the effect of polygenic risk scores (PRSs) derived from individuals of European (EUR) ancestry on common diseases among individuals of South Asian (SAS) ancestry in the UK Biobank (UKB). Additionally, we studied the interaction between PRS and family history (FH) in the same population. <h4>Methods</h4> To calculate the PRS, we used a previously published panel of...

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Literature Corpus work: 24d8258a-e235-5483-ae77-24beaf899f23
DOI: 10.1101/2023.03.20.23287470

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