Article

Transferability of European-derived cardiometabolic polygenic risk scores in the South Asians and their interplay with family history

2023-04-18

Abstract excerpt

<h4>Background: </h4> & Aims: We aimed to investigate the transferability of European-derived polygenic risk scores (PRSs) for common metabolic diseases such as coronary artery disease (CAD), obesity, and type 2 diabetes (T2D) to South Asian (SAS) individuals in the UK Biobank. Additionally, we studied the interaction between PRS and family history (FH) in the same population. <h4>Methods: </h4> To calculate the P...

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Literature Corpus work: 51993184-d223-5f0a-8306-a773e3b43977
DOI: 10.21203/rs.3.rs-2752714/v1

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