Article

Widespread recessive effects on common diseases in a cohort of 44,000 British Pakistanis and Bangladeshis with high autozygosity

2024-04-03

Abstract excerpt

Genetic association studies have focused on testing additive models in cohorts with European ancestry. Little is known about recessive effects on common diseases, specifically for non-European ancestry. Genes & Health is a cohort of British Pakistani and Bangladeshi individuals with elevated rates of consanguinity and endogamy, making it suitable to study recessive effects. We imputed variants into 44,190 genotype...

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Literature Corpus work: 02bf9de0-2a12-53fd-b6d5-e39a92784f73
DOI: 10.1101/2024.04.03.24305256

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