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Article

Transferability of genetic loci and polygenic scores for cardiometabolic traits in British Pakistani and Bangladeshi individuals.

Nature communications - 9 Aug 2022

Huang Qin Qin, Sallah Neneh, Dunca Diana, Trivedi Bhavi, Hunt Karen A, Hodgson Sam, Lambert Samuel A, Arciero Elena, Wright John, Griffiths Chris, Trembath Richard C, Hemingway Harry, Inouye Michael, Finer Sarah, van Heel David A, Lumbers R Thomas, Martin Hilary C, Kuchenbaecker Karoline

Abstract excerpt

Individuals with South Asian ancestry have a higher risk of heart disease than other groups but have been largely excluded from genetic research. Using data from 22,000 British Pakistani and Bangladeshi individuals with linked electronic health records from the Genes & Health cohort, we conducted genome-wide association studies of coronary artery disease and its key risk factors. Using power-adjusted...

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Identifiers

PMID: 35945198
DOI: 10.1038/s41467-022-32095-5
PMCID: PMC9363492

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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