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Article

Polygenic Risk Score Assessment for Coronary Artery Disease in Asian Indians.

Journal of cardiovascular translational research - 1 Oct 2024

Rout Madhusmita, Tung Gurleen Kaur, Singh Jai Rup, Mehra Narinder Kumar, Wander Gurpreet S, Ralhan Sarju, Sanghera Dharambir K

Abstract excerpt

We evaluated the performance of various polygenic risk score (PRS) models derived from European (EU), South Asian (SA), and Punjabi Asian Indians (AI) studies on 13,974 subjects from AI ancestry. While all models successfully predicted Coronary artery disease (CAD) risk, the AI, SA, and EU + AI were superior predictors and more transportable than the EU model; the predictive performance in training and test sets...

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Identifiers

PMID: 38658478
DOI: 10.1007/s12265-024-10511-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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