Article

Harnessing the power of polygenic risk scores to predict type 2 diabetes and its subtypes in a high-risk population of British Pakistanis and Bangladeshis in a routine healthcare setting

2021-07-16

Abstract excerpt

<h4>Background</h4> Type 2 diabetes is highly prevalent in British Pakistanis and Bangladeshis (BPB). The Genes & Health (G&H) cohort offers means to explore genetic determinants of disease in BPBs. <h4>Methods</h4> We assessed whether common genetic loci associated with type 2 diabetes in European-ancestry individuals (EUR) replicate in G&H. We constructed a type 2 diabetes polygenic risk score (PRS) and combined...

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Literature Corpus work: 0443fc03-8140-503a-b66e-51207c1ab364
DOI: 10.1101/2021.07.12.21259837

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