Article

An atlas of associations between polygenic risk scores from across the human phenome and circulating metabolic biomarkers

2021-10-25

Abstract excerpt

Polygenic risk scores (PRS) are becoming an increasingly popular approach to predict complex disease risk, although they also hold the potential to develop insight into the molecular profiles of patients with an elevated genetic predisposition to disease. In this study, we have constructed an atlas of associations between 129 different PRS and 249 circulating metabolites in up to 83,004 participants from the UK Bi...

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Literature Corpus work: 360d8621-e673-5001-bf8b-a9c7e7d3ed8e
DOI: 10.1101/2021.10.14.21265005

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