Article

Poly-Exposure and Poly-Genomic Scores Implicate Prominent Roles of Non-Genetic and Demographic Factors in Four Common Diseases in the UK

2019-11-08

Abstract excerpt

<h4>ABSTRACT</h4> While polygenic risk scores (PRSs) have been shown to identify a small number of individuals with increased clinical risk for several common diseases, non-genetic factors that change during a lifetime, such as lifestyle, employment, diet, and pollution, have a larger role in clinical prediction. We analyzed data from 459,613 participants of the UK Biobank to investigate the independent and combi...

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Literature Corpus work: ba0d319a-1d9f-5a69-aeb4-095a07b64326
DOI: 10.1101/833632

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