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Article

Multiomic blood correlates of genetic risk identify presymptomatic disease alterations.

Proceedings of the National Academy of Sciences of the United States of America - 1 Sept 2020

Wainberg Michael, Magis Andrew T, Earls John C, Lovejoy Jennifer C, Sinnott-Armstrong Nasa, Omenn Gilbert S, Hood Leroy, Price Nathan D

Abstract excerpt

Transitions from health to disease are characterized by dysregulation of biological networks under the influence of genetic and environmental factors, often over the course of years to decades before clinical symptoms appear. Understanding these dynamics has important implications for preventive medicine. However, progress has been hindered both by the difficulty of identifying individuals who will eventually go...

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Identifiers

PMID: 32817414
DOI: 10.1073/pnas.2001429117
PMCID: PMC7474629

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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