Article

A Patient-Derived Tumoroid Platform for NF1 Low-Grade Glioma shows Myeloid Evolution and Shifting Metabolic Dependencies in vitro

2026-03-25

Abstract excerpt

<title>Abstract</title> <p> About 10–15% of individuals with Neurofibromatosis Type 1 develop a low-grade glioma (LGG) within the optic pathway, and an additional 3–5% of individuals develop LGG outside of the optic pathway. In recent years molecular analysis has greatly enhanced our understanding of what drives these NF1 LGG; however, to date <italic>in vitro</italic> and <italic>in vivo</italic> models are...

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Literature Corpus work: 35fb2871-ace9-52be-a172-c85d1593804a
DOI: 10.21203/rs.3.rs-9118779/v1

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