Article

Longitudinal multi-omics characterization of the malignant evolution in multirelapsing glioblastoma

2026-06-22

Abstract excerpt

Linking glioblastoma (GBM) evolution to clinical progression is challenged by multiple factors, including tumor location for repeated sample collection, and short patient survival. In a single individual, we collected and analysed samples from 11 operations distributed across 31 months of multi-relapsing and multifocal GBM, including terminal leptomeningeal progression. All samples shared genomic ancestry of the r...

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Literature Corpus work: 56d245fb-6a08-5618-9719-a2d19eb2012b
DOI: 10.64898/2026.06.11.26355035

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