Article
UPF3A is a ubiquitously expressed NMD factor among mouse tissues
2023-02-07
Abstract excerpt
Nonsense-mediated mRNA decay (NMD), an important post-transcriptional regulatory mechanism in gene expression, is actively involved in a series of cellular and physiological processes, thus controlling cell fate and tissue homeostasis. Defects in NMD cause human diseases such as neurodevelopmental disorders, tumorigenesis and autoimmunity. UPF3 (Up- frameshift protein 3), first identified in the baker’s yeast, is...
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Identifiers and source
- Literature Corpus work
- 35e2f670-0532-568f-8a11-d8c00c908bcb
- DOI
- 10.1101/2023.02.06.526166
