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Article

UPF3A is a ubiquitously expressed NMD factor among mouse tissues

2023-02-07

Abstract excerpt

Nonsense-mediated mRNA decay (NMD), an important post-transcriptional regulatory mechanism in gene expression, is actively involved in a series of cellular and physiological processes, thus controlling cell fate and tissue homeostasis. Defects in NMD cause human diseases such as neurodevelopmental disorders, tumorigenesis and autoimmunity. UPF3 (Up- frameshift protein 3), first identified in the baker’s yeast, is...

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Literature Corpus work
35e2f670-0532-568f-8a11-d8c00c908bcb
DOI
10.1101/2023.02.06.526166
Open publication

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UPF3A is a ubiquitously expressed NMD factor among mouse tissuesDOI 10.1101/2023.02.06.526166
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