Article

CRISPR/Cas9-Mediated Gene-Knockout of <em>UPF3B</em> Alters Expression of Cell Cycle and Neuron-Specific Genes

2021-11-01

Abstract excerpt

UPF3B is a constituent of the classical nonsense-mediated mRNA decay (NMD) pathway that degrades both the aberrant transcripts and a set of physiological transcripts. In higher eukaryotes, UPF3B have significant biochemical functions in diverse cellular processes including NMD and translation. UPF3B plays a crucial role in neuronal development and differentiation. Next-generation sequencing technologies identified...

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Literature Corpus work: 85b99d67-f341-5c14-a2ba-31dd849e97af
DOI: 10.20944/preprints202111.0013.v1

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