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Single‐cell RNA‐Seq reveals the earliest lineage specification and X chromosome dosage compensation in bovine preimplantation embryos

16 Feb 2024

Abstract excerpt

Lineage specification and X chromosome dosage compensation are two crucial biological processes that occur during preimplantation embryonic development. Although extensively studied in mice, the timing and regulation of these processes remain elusive in other species, including humans. Previous studies have suggested conserved principles of human and bovine early development. This study aims to provide...

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PMID: 38363564
DOI: 10.1096/fj.202302035rr

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