Article

Kinetic Monitoring Of Neuronal Stress Response To Proteostasis Dysfunction

2021-05-24

Abstract excerpt

<h4>ABSTRACT</h4> Proteostasis dysfunction and activation of the unfolded protein response (UPR) are characteristic of all major neurodegenerative diseases. Nevertheless, although the UPR and proteostasis dysfunction has been studied in great detail in model organisms like yeast and mammalian cell lines, it has not yet been examined in neurons. In this study, we applied a viral vector-mediated expression of a rep...

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Literature Corpus work: 353fccfe-2e0d-531a-a7d2-7738339d76f8
DOI: 10.1101/2021.05.24.445437

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