Article

Localized molecular chaperone synthesis maintains neuronal dendrite proteostasis

2023-12-11

Abstract excerpt

<title>Abstract</title> <p>Proteostasis is maintained through regulated protein synthesis and degradation and chaperone-assisted protein folding. However, this is challenging in neuronal projections because of their polarized morphology and constant synaptic proteome remodeling. Using high-resolution fluorescence microscopy, we discovered that neurons localize a subset of chaperone mRNAs to their dendrites and us...

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Literature Corpus work: b43adfd3-e247-5892-8de7-d4166e15050a
DOI: 10.21203/rs.3.rs-3673702/v1

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