Article

Hierarchical Markov Random Field model captures spatial dependency in gene expression, demonstrating regulation via the 3D genome

2019-12-17

Abstract excerpt

<h4> A bstract </h4> HiC technology has revealed many details about the eukaryotic genome’s complex 3D architecture. It has been shown that the genome is separated into organizational structures which are associated with gene expression. However, to the best of our knowledge, no studies have quantitatively measured the level of gene expression in the context of the 3D genome. Here we present a novel model that...

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Literature Corpus work: 352722d7-70bf-5fda-a439-c69cd652b0cd
DOI: 10.1101/2019.12.16.878371

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