Article

Regulation associated modules reflect 3D genome modularity associated with chromatin activity

2022-03-04

Abstract excerpt

<h4>ABSTRACT</h4> The 3D genome has been shown to be organized into modules including topologically associating domains (TADs) and compartments that are primarily defined by spatial contacts from Hi-C or other experiments. There exists a gap to investigate whether and how the spatial modularity of the chromatin is related to the functional modularity resulting from the chromatin activity. Increasing evidence show...

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Literature Corpus work: f8d3f950-1072-5e31-a256-ca2ee219a770
DOI: 10.1101/2022.03.02.482718

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