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Comparing 3D genome organization in multiple species using Phylo-HMRF

2019-02-19

Abstract excerpt

Recent developments in whole-genome mapping approaches for the chromatin interactome (such as Hi-C) have offered new insights into 3D genome organization. However, our knowledge of the evolutionary patterns of 3D genome structures in mammalian species remains surprisingly limited. In particular, there are no existing phylogenetic-model based methods to analyze chromatin interactions as continuous features across d...

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Literature Corpus work
ce3e4e6b-2c07-5c53-be80-497ad0689079
DOI
10.1101/552505
Open publication

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