Article

Dynamic Network Analysis of the 4D Nucleome

2018-02-20

Abstract excerpt

<h4>Motivation</h4> For many biological systems, it is essential to capture simultaneously the function, structure, and dynamics in order to form a comprehensive understanding of underlying phenomena. The dynamical interaction between 3D genome spatial structure and transcriptional activity creates a genomic signature that we refer to as the four-dimensional organization of the nucleus, or 4D Nucleome (4DN). The...

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Literature Corpus work: a53cceaa-373e-59c4-a7b3-64a3af1790fd
DOI: 10.1101/268318

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