Back to search

Article

Intra- and inter-chromosomal chromatin interactions mediate genetic effects on regulatory networks

2017-08-03

Abstract excerpt

<h4>Summary</h4> Genome-wide studies on the genetic basis of gene expression and the structural properties of chromatin have considerably advanced our understanding of the function of the human genome. However, it remains unclear how structure relates to function and, in this work, we aim at bridging both by assembling a dataset that combines the activity of regulatory elements (e.g. enhancers and promoters), exp...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
98aaac0d-3c30-5ee1-9e56-05eb3805bf45
DOI
10.1101/171694
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Intra- and inter-chromosomal chromatin interactions mediate genetic effects on regulatory networksDOI 10.1101/171694
Select a neighboring publication to make it the new centre.