Article

Modeling gene expression networks to predict interchromosomal organization during human embryonic stem cell differentiation

2018-05-10

Abstract excerpt

Cellular differentiation occurs through the regulation of lineage-specific gene expression networks that are facilitated by the spatial organization of the genome. Although techniques based on the chromatin conformation capture (3C) approach have yielded intrachromosomal genome-wide interaction maps, strategies to identify non-random interchromosomal associations is lacking. Therefore, we modeled the genomic organ...

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Literature Corpus work: 443e02e1-fa83-5f82-aad2-2dfd55027785
DOI: 10.1101/318899

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