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Article

Mendelian Randomization Identified CHRNE as a Potential Drug Target for Alzheimer’s disease

2022-08-22

Abstract excerpt

<title>Abstract</title> <p>Since clinical trials of novel therapeutics for Alzheimer’s disease (AD) have been largely disappointing, drug repurposing may provide an effective approach to identifying therapeutics to treat AD. In this study, two-sample Mendelian randomization analysis was employed to evaluate brain and blood transcriptomic data for 1263 actionable proteins targeted by approved drugs or in the clini...

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Literature Corpus work
350ff0ab-c0d5-5b6f-a3c8-10fd7f8c2e45
DOI
10.21203/rs.3.rs-1940818/v1
Open publication

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Mendelian Randomization Identified CHRNE as a Potential Drug Target for Alzheimer’s diseaseDOI 10.21203/rs.3.rs-1940818/v1
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