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Multicomponent Mendelian randomization and machine learning studies of potential drug targets for neurodegenerative diseases

2025-04-18

Abstract excerpt

<title>Abstract</title> <p>Neurodegenerative diseases (NDDs) remain a global health challenge. Alzheimer's disease (AD) and Parkinson's disease (PD) are the main types of NDDs worldwide, and Mendelian Randomization (MR) analysis across multi-omics and the entire genome offers novel strategies for identifying potential drug targets. This study used MR and summary-based MR(SMR) analysis to explore the causal relati...

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Literature Corpus work
85622baf-867d-5e27-b7c7-f1b0b97f2c41
DOI
10.21203/rs.3.rs-5848172/v1
Open publication

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Multicomponent Mendelian randomization and machine learning studies of potential drug targets for neurodegenerative diseasesDOI 10.21203/rs.3.rs-5848172/v1
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