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Article

Identification of potential drug targets for Alzheimer's disease from genetic insights: A Mendelian randomization study.

Medicine - 30 Jan 2026

Zhao Yan-Hong, Ning Jing-Hua, Zhang Xin, Qu Run, Lv Cong-Cong, Zhang Yu-Zhe

Abstract excerpt

Alzheimer disease (AD) is a primary neurodegenerative disorder of the brain with an unknown cause and complex pathogenesis. It is the most common form of dementia and poses a significant threat to the health of the aging population worldwide. However, effective pharmacological treatments remain limited. This study employed publicly available genome-wide association study summary statistics, which included 4907...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41630303
DOI: 10.1097/MD.0000000000045715
PMCID: PMC12863894

Genes

APOE
CCL21
CD55
CSF3
LGMN
MICB
PEBP1
PHGDH
TGM1
TNFAIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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