Article

Short-Chain Polyphosphates Induce Tau Fibrillation and Neurotoxicity in Human iPSC-Derived Retinal Neurons

2024-12-02

Abstract excerpt

<title>Abstract</title> <p>The onset of Alzheimer’s Disease and Frontotemporal Dementia is closely associated with the aggregation of tau, a multifunctional protein essential for neuronal stability and function. Given the role of tau aggregation in neurodegeneration, understanding the mechanisms behind its fibrils formation is crucial for developing therapeutic interventions to halt or reverse disease progression...

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Literature Corpus work: 34607e3e-b39f-5604-8140-47208100ee7b
DOI: 10.21203/rs.3.rs-5409787/v1

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Short-Chain Polyphosphates Induce Tau Fibrillation and Neurotoxicity in Human iPSC-Derived Retinal NeuronsDOI 10.21203/rs.3.rs-5409787/v1Read

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