Article

New base editors facilitate C-to-G transversions in Nicotiana benthamiana

2025-03-31

Abstract excerpt

<title>Abstract</title> <p>Base editors, including cytosine base editor (CBE) and adenine base editor, are widely used in plants to induce base transitions. Recently, glycosylase base editor (GBE) have been developed to induce C-to-G transversions but within a narrow editing window in human cells. Here, we describe six plant GBEs (GBE1-GBE6) composed of Cas9 nickase, human APOBEC3A, Escherichia coli-derived uraci...

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Literature Corpus work: 33947a42-d58a-563b-ab80-4c14ad7b4ef1
DOI: 10.21203/rs.3.rs-6149764/v1

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