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Breaking genetic shackles: The advance of base editing in genetic disorder treatment

6 Mar 2024

Abstract excerpt

The rapid evolution of gene editing technology has markedly improved the outlook for treating genetic diseases. Base editing, recognized as an exceptionally precise genetic modification tool, is emerging as a focus in the realm of genetic disease therapy. We provide a comprehensive overview of the fundamental principles and delivery methods of cytosine base editors (CBE), adenine base editors (ABE), and RNA base...

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PMID: 38510648
DOI: 10.3389/fphar.2024.1364135

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