Back to search

Article

Differential requirements for different subfamilies of the mammalian SWI/SNF chromatin remodeling enzymes in myoblast differentiation

2023-03-05

Abstract excerpt

Mammalian SWI/SNF (mSWI/SNF) complexes are ATP-dependent chromatin remodeling enzymes that are critical for normal cellular functions and that are mis-regulated in ∼20% of human cancers. These enzymes exhibit significant diversity in the composition of individual enzyme complexes. mSWI/SNF enzymes are classified into three general sub-families based on the presence or absence of specific subunit proteins. The thre...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
32c1ab4b-3162-5a69-a494-264f89c7ef41
DOI
10.1101/2023.03.05.531193
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Differential requirements for different subfamilies of the mammalian SWI/SNF chromatin remodeling enzymes in myoblast differentiationDOI 10.1101/2023.03.05.531193
Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomicsSemantic proximity
The Many Roles of BAF (mSWI/SNF) and PBAF Complexes in Cancer.Semantic proximity
Composition and Function of Mammalian SWI/SNF Chromatin Remodeling Complexes in Human Disease.Semantic proximity
The BAF complex in development and diseaseSemantic proximity
Mammalian SWI/SNF complexes in cancer: emerging therapeutic opportunities.Semantic proximity
Essential Role of ARID2 Protein-containing SWI/SNF Complex in Tissue-specific Gene ExpressionSemantic proximity
Molecular pathways: SWI/SNF (BAF) complexes are frequently mutated in cancer--mechanisms and potential therapeutic insights.Semantic proximity
The SWI/SNF Complex: A Frequently Mutated Chromatin Remodeling Complex in Cancer.Semantic proximity
The BRG1 ATPase of Human SWI/SNF Chromatin Remodeling Enzymes as a Driver of CancerSemantic proximity
Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy.Semantic proximity
BAFfling pathologies: Alterations of BAF complexes in cancer.Semantic proximity
(mis)-Targeting of SWI/SNF complex(es) in cancer.Semantic proximity
Select a neighboring publication to make it the new centre.