Article
Essential Role of ARID2 Protein-containing SWI/SNF Complex in Tissue-specific Gene Expression
20 Dec 2011
Abstract excerpt
Unfolding of the gene expression program that converts precursor cells to their terminally differentiated counterparts is critically dependent on the nucleosome-remodeling activity of the mammalian SWI/SNF complex. The complex can be powered by either of two alternative ATPases, BRM or BRG1. BRG1 is critical for development and the activation of tissue specific genes and is found in two major stable...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
