(mis)-Targeting of SWI/SNF complex(es) in cancer.

doi:10.1007/s10555-023-10102-5

Back to search

Article

(mis)-Targeting of SWI/SNF complex(es) in cancer.

Cancer metastasis reviews - 1 Jun 2023

Reddy Divya, Bhattacharya Saikat, Workman Jerry L

Abstract excerpt

The ATP-dependent chromatin remodeling complex SWI/SNF (also called BAF) is critical for the regulation of gene expression. During the evolution from yeast to mammals, the BAF complex has evolved an enormous complexity that contains a high number of subunits encoded by various genes. Emerging stu...

Topics

Animals
Humans
Transcription Factors
Neoplasms
Mutation
Chromatin Assembly and Disassembly
Mammals

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.