Article
Aurora-A Kinase Maintains the Fidelity of Early and Late Mitotic Events in HeLa Cells
1 Dec 2003
Abstract excerpt
Aurora-A, a member of the Aurora/Ipl1-related kinase family, is overexpressed in various types of cancer and considered to play critical roles in tumorigenesis. To better understand the pathological effect of Aurora-A activation, it is first necessary to elucidate the physiological functions of Aurora-A. Here, we have investigated the roles of Aurora-A in mitotic progression with the small interfering RNA,...
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